In the synthesis of aspirin, sulfuric acid is also used as a catalyst to speed up the reaction (wikipedia, sulfuric acid, 2013) discussion: sources of error that were possibly present in the synthesis of aspirin lab are an improperly calibrated balance, an inaccurate hot plate, contamination of the. Synthesis of aspirin from methyl salicylate introduction the synthesis of aspirin (acetyl salicyclic acid) began with methyl these mechanisms for this experiment can be seen in scheme 1 aspirin is classified as a non-steroidal anti-inflammatory drug that is indicated for heart attack, pain, and fever. Practical 2 : organic synthesis - aspirin aims the purpose of this experiment is: the purpose of this experiment is to synthesize the drug aspirin from salicylic acid and acetic anhydride mixture, to examine the purity of aspirin by carrying out chemical testing and also to determine the yield.
Aspirin, also known as acetylsalicylic acid (asa), is a medication used to treat pain, fever, or inflammation specific inflammatory conditions in which aspirin is used include kawasaki disease. Synthesis of aspirin 2 chemicals used sample purpose salicylic acid starting material acetic anhydride starting material, serves also as the solvent phosphoric acid catalyst water used to destroy unreacted acetic anhydride precipitates crude aspirin ethanol recrystallizing solvent acetylsalicylic. The synthesis of aspirin chemistry standard level lab report data collection and processing and conclusion and evaluation date: december 8th, 2011 purpose: the purpose of this lab was to synthesize aspirin, determine the theoretical yield, compare the percent yield to the theoretical yield. Synthesis of aspirin notes history and application aspirin is one of the most commonly used drugs in the world with approximately 100 billion tablets1 being safety precautions9,10 acetic anhydride is corrosive, reacts violently with water, is toxic by inhalation, harmful by ingestion and a lachrymator.
Aspirin synthesis your team of scientists has been hired by the drug research division of santa monica pharmaceuticals, a new start-up company such a route might improve efficiency, but it would also increase the complexity of the synthesis because of the additional safety precautions that. Titration of synthesized aspirin a continuation of the aspirin synthesis lab addition of fecl3 to salicylic acid will result in the formation of a deeply purple colored complex 5 safety precautions. Such a route might improve efficiency, but it would also increase the complexity of the synthesis because of the additional safety precautions that purification strategies can often be as complex as the syntheses themselves in the first part of the lab your team will make aspirin, purify your product. Aspirin, acetylsalicylic acid, was first synthesized in 1893 by felix hofmann, a chemist for the german firm of bayer the degree of lowering of the melting point depends on the nature and the concentration of the impurities safety precautions.
In most organic synthesis laboratories, synthesis of aspirin (acetylsalicylic acid) is a part of the curriculum for many undergraduate students (figure 1) these courses are designed be sure to take all necessary safety precautions and carefully add 1 or 2 drops of the catalyst, 85% phosphoric acid. . Aspirin is an analgesic, non-steroidal anti-inflammatory drug which is used widely for the treatment of fever, inflammation and mild to moderate pain aspirin also plays a key role in the treatment of inflammatory diseases such as rheumatoid arthritis (a progressive autoimmune disease primarily.
In this experiment aspirin, also known as acetylsalicylic acid, was synthesized from salicylic acid and acetic anhydride in the reaction the hydroxyl group on the benzene ring in salicylic acid reacted with acetic anhydride to form an ester functional group this method of forming acetylsalicylic acid is an. The synthesis of aspirin was performed and then two tests were used to determine the relative purity of the aspirin we synthesized in performing this experiment, proper safety precautions were followed and protocols were reviewed prior to running this experiment lab safety goggles, gloves and. Synthesis of aspirin:- aspirin can be made by reacting salicylic acid with acetic acid in the presence of an acid catalyst.
The synthesis of aspirin demonstrated here demonstrates several relevant suggestions that should be considered in the synthesis of a substance firstly, the recrystallization of a product should be performed if possible and relevant in most reactions, the amount of product exceeds the impurities. 8 synthesis of aspirin uploaded by chelsea reyna tolentino aspirin is an effective analgesic (pain reliever), antipyretic (fever reducer) and anti-inflammatory agent and is one of the most widely used non-prescription drugs keep this compound under the hood at all timessafety precautions. Experimental procedure: synthesis of aspirin the synthesis of aspirin was performed and then two tests were used to determine the relative purity of the aspirin we synthesized in performing this experiment, proper safety precautions were followed and protocols were reviewed prior to running.
The aspirin product is not very soluble in water so the aspirin product will precipitate when water is added the synthesis reaction of aspirin is the spectroscopic analysis of aspirin will involve the complexing of iron(iii) to the deprotonated form of salicylic acid (salicylate ion) to give a purple solution. Introduction aspirin (acetylsalicylic acid) is a synthetic organic derived from salicylic acid a german chemist named felix hoffman is credited with being the first to synthesize aspirin in 1897 hoffman's father had severe arthritis but could not tolerate salicylic acid he was taking for pain relief. Synthesis of aspirin aspirin is the single most manufactured drug in the world aspirin's chemical name is acetylsalicyl-ic acid, and it is synthesized from the reaction of acetic anhydride with salicylic acid in the presence of phosphoric acid as a catalyst. Safety precautions for synthesis of acetic anhydride acetic anhydride acetic anhydride is an irritant and also flammable, therefore gloves and discussion the synthesis of aspirin demonstrated here demonstrates several relevant suggestions that should be considered in the synthesis of a substance.